Cortisol Profile

Why am I having this test?
Your consultant/specialist doctor/nurse have decided that it is necessary for you to undergo a series of blood tests, so we can monitor the effectiveness of your Hydrocortisone treatment.

Who carries out this test?
A nurse who specialises in endocrinology is responsible for carrying out this test.

Where is the test carried out?
You will be sent a letter with details of the test and which department you will need to attend. If you wish you may bring a companion with you.

How long will the test take?
The test takes approximately 7½ hours to complete. You may wish to bring a book/magazine/activity with you.

What do I need to do before the test?

• You may eat and drink as usual.
• If you are taking the contraceptive pill or hormone replacement therapy (HRT), it may be necessary to stop these 8 weeks prior to the test, as it interferes with the interpretation of the result. Please let the nurse know on receipt of your appointment letter.
• Do not take your hydrocortisone medicine on the morning of the test, but please bring it with you. The nurse will tell you when to take your medicine.
• If you take steroid inhalers, steroid nasal sprays, steroid creams or other steroid medication, please let the nurse know on receipt of your appointment letter.
• All other medication should be taken as usual.

What happens during the test?

• On arrival you will meet the nurse who is responsible for the test. The nurse will explain the test and you will be given the opportunity to ask questions prior to the start of the test.
• A cannula, a fine plastic tube, will be inserted into a vein in your arm. This is used to take blood samples. There may be some discomfort for a few seconds.
• A blood sample is taken initially; further samples are then taken at hourly intervals during the course of the day for 7 hours by the nurse.
• If you take a lunchtime dose of hydrocortisone you will be asked to take this as usual.
• You may eat and drink normally during the course of the test and will be provided with a packed lunch.
• At the end of the test, the cannula will be removed, and a small dressing applied. This may be removed when you get home.

Are there any side effects?
After the test, you may have a small bruise where the needle went in. Bruises can be painful, but are usually harmless and fade over the next few days.

What happens after the test?

• On completion of the test you will be safe to resume your normal daily activities.
• If you have been asked to stop any medicines prior to the test, the nurse will let you know when to restart the tablets.
• Based on the results of the test, your specialist doctor/nurse will be able to decide on the effectiveness of your treatment.
• The results will be discussed at your next clinic visit or a letter will be sent to you and your GP.
• The nurse looking after you will arrange a further appointment as required.

If you require more details please contact the Specialist Nurses in Endocrinology:
Tel: 01274 382019 Monday – Friday between 8.00am and 4.00pm except Bank Holidays